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Citadines Millennium Ortigas Manila is strategically located within the Ortigas Center, a building home to esteemed multinational and Filipino corporations. These include the Asian Development Bank, Jollibee Food Corporation, Meralco and San Miguel Corporation.

The Apart’hotel, which stands apart from other Ortigas Center hotels for the plush amenities and facilities on offer, is also conveniently located a short distance away from shopping malls such as SM Megamall and Robinsons Galleria. The Medical City, an internationally accredited medical facility, is also in the vicinity.